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Tirzepatide Providers in Missouri

21 listed in Missouri · Listings last verified October 2026 · How we vet listings

We list tirzepatide providers across Missouri, mainly in St. Louis, Cape Girardeau and Kansas City (21 in total). Tirzepatide is the medicine in Zepbound and Mounjaro. Most listings are medical weight loss clinics, plus some primary care and diabetes practices. Compare the listings below, then call the practice to ask about insurance, costs and new-patient openings.

Tirzepatide (Zepbound, Mounjaro) providers in Missouri are mostly medical weight loss clinics, with the largest group in the St. Louis area. Our list includes only providers whose own website or Google listing names tirzepatide.

What it is

Tirzepatide is a once-weekly prescription shot made by Eli Lilly. It acts on two gut hormones, GIP and GLP-1, that help control appetite and blood sugar. It's sold under two brand names:

  • Zepbound is approved for weight loss and keeping weight off. It's also approved to treat moderate to severe obstructive sleep apnea in adults with obesity [1].
  • Mounjaro is approved for adults with type 2 diabetes [3].

Zepbound comes as a single-dose pen, a vial or a multi-dose KwikPen that holds 4 weekly doses. You start at 2.5 mg and go up by 2.5 mg at least every 4 weeks, to a maintenance dose of 5, 10 or 15 mg [1]. The label has a boxed warning about thyroid tumors seen in animal studies [1].

Who it's for

Zepbound is for adults with obesity, or with overweight plus at least one weight-related health problem, such as high blood pressure or high cholesterol. It's also for adults with obesity who have moderate to severe sleep apnea [1].

It's used along with a lower-calorie diet and more activity. Most people stay on it long term, because weight often returns after stopping.

Mounjaro is for adults with type 2 diabetes. If you have diabetes, your doctor will usually start there, since diabetes coverage is easier to get.

Tirzepatide isn't right for everyone. Tell your provider if you or a family member has had medullary thyroid cancer or MEN 2, or if you've had pancreatitis [1]. It isn't approved for people under 18 [1].

Cost and coverage

Commercial insurance. If your plan covers Zepbound pens, the savings card can bring your cost to as little as $25 a fill. It pays up to $100 a month and $1,300 a year [2]. Mounjaro's card works the same way, paying up to $150 a month for covered patients [3]. Both cards end December 31, 2026 [2][3].

Self-pay. Lilly sells the Zepbound KwikPen and vials for $299 a month at 2.5 mg and $399 at 5 mg. Higher doses are $449 a month if you refill within 45 days. If you wait longer, the price goes up to $499 for 7.5 mg and $699 for 10 to 15 mg [2].

Medicare. From July 1, 2026, through December 31, 2027, the Medicare GLP-1 Bridge covers the Zepbound KwikPen for $50 a month. Single-dose pens and vials aren't included. You need Part D coverage, prior approval and a qualifying BMI. If you have type 2 diabetes or moderate to severe sleep apnea, you're not eligible for the Bridge, but your Part D plan may cover tirzepatide [4].

Medicaid. States must cover these drugs for diabetes but can choose whether to cover them for weight loss [5].

For more, see our Zepbound savings guide, how Zepbound works and GLP-1 guides.

St. Louis area

Advanced Medical Weight loss at the Crothers Institute

Weight Loss

Practice rating 4.5 (20 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
12633 Olive Blvd, Creve Coeur 63141
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Global Obesity and Wellness Care

Weight Loss

Practice rating 5.0 (14 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
13990 Olive Blvd #102, Chesterfield 63017
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Morningstar Neuropathy & Pain Treatment Center, LLC

Weight Loss

Practice rating 4.3 (16 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
4710 Mexico Rd Ste C, St. Peters 63376
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

PremierU Med – South County

Weight Loss

Practice rating 4.9 (98 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
4109 Union Rd, St. Louis 63129
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Saint Louis Medical Weight Loss, LLC

Weight Loss

Practice rating 4.7 (3 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
4455 Telegraph Rd Ste 260, St. Louis 63129
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Simply Wurth It Medical Weight Loss – O’Fallon

Weight Loss

Practice rating 4.8 (21 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
856 Waterbury Falls Dr, O'Fallon 63368
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Simply Wurth It Medical Weight Loss – South County

Weight Loss

Practice rating 5.0 (42 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
5139 Mattis Rd Suite 101, St. Louis 63128
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Simply Wurth It Medical Weight Loss – St. Peters

Weight Loss

Practice rating 5.0 (125 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
5301 Veterans Memorial Pkwy Ste 102, St. Peters 63376
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Simply Wurth It Medical Weight Loss – Wentzville

Weight Loss

Practice rating 5.0 (325 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
112 Creekside Office Dr, Wentzville 63385
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

The Health & Wellness Center

Weight Loss

Practice rating 4.7 (336 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
9717 Landmark Pkwy Dr Ste 115, St. Louis 63127
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Cape Girardeau area

BMI- Bariatric & Metabolic Institute : Vishon J Subramani, M.D.

Weight Loss

Practice rating 4.7 (50 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
125 S Broadview St Ste 2, Cape Girardeau 63703
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Optimize U – Cape Girardeau | Hormone & Cryotherapy Clinic

Weight Loss

Practice rating 5.0 (101 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
332 S Silver Springs Rd, Cape Girardeau 63703
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Kansas City area

4 Life Weight Loss Centers, Inc.

Weight Loss

Practice rating 5.0 (2 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
17331 E 40 Hwy Suite 103, Independence 64055
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Hormone Treatment Centers – Lee’s Summit, MO

Weight Loss

Practice rating 5.0 (26 Google reviews)

  • Tirzepatide
Address
232 NE Tudor Rd, Lee's Summit 64086
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Meta-Health Weight Management

Weight Loss

Practice rating 5.0 (1 Google review)

  • Semaglutide
  • Tirzepatide
Address
617 Harborview Dr, Smithville 64089
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Slim4Life Weight Loss Center – Independence

Weight Loss

Practice rating 4.9 (67 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
18931 E Valley View Pkwy F, Independence 64055
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Columbia–Jefferson City area

Vitality Medical Group

Weight Loss

Practice rating 3.9 (12 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
107 S Maple St, Eldon 65026
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Joplin area

Optimized Health

Weight Loss

Practice rating 5.0 (208 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
2727 E 32nd St #9, Joplin 64804
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

How to choose a provider

Look for real medical care. A good provider reviews your health history, orders lab work when needed and checks in as your dose goes up. Ask who handles side effects like nausea, and how often you'll be seen.

Ask what they prescribe. Ask if they prescribe brand-name Zepbound or Mounjaro. Some businesses sell compounded "tirzepatide" instead. Compounded drugs are not FDA approved, and FDA has had reports of people hurt by dosing mistakes [6]. FDA declared the tirzepatide shortage over in December 2024 [7]. Our list doesn't include businesses that market compounded GLP-1s.

Ask about the paperwork. Ask if they'll handle prior approval with your insurer. If you have sleep apnea, ask whether they can document it. That's a separate approved use that some plans cover.

Confirm the basics yourself. Call to check insurance, new-patient openings and telehealth. We don't verify these.

Frequently asked questions

Are Zepbound and Mounjaro the same drug?

Yes. Both are tirzepatide, made by Eli Lilly, with the same dose steps. Zepbound is approved for weight loss and for sleep apnea in adults with obesity. Mounjaro is approved for type 2 diabetes. Because the approved uses differ, insurance plans cover them under different rules.

How much does Zepbound cost without insurance?

Lilly sells the Zepbound KwikPen and vials for $299 a month at 2.5 mg, $399 at 5 mg and $449 at higher doses if you refill within 45 days. If you refill later, higher doses cost $499 to $699 a month. Prices can change, so check Lilly's site before you fill.

Does Medicare cover Zepbound?

Often, yes. From July 2026 through December 2027, the Medicare GLP-1 Bridge covers the Zepbound KwikPen for $50 a month for eligible people with Part D. You need prior approval and a qualifying BMI. People with sleep apnea or type 2 diabetes go through their regular Part D plan instead.

Is compounded tirzepatide safe?

FDA says compounded drugs are not FDA approved, and the agency doesn't check them for safety, quality or effectiveness. FDA has received reports of people hospitalized after dosing errors. The tirzepatide shortage ended in December 2024, and brand-name Zepbound is now sold at self-pay prices.

How is tirzepatide taken?

Zepbound and Mounjaro are shots you give yourself under the skin once a week. You start at 2.5 mg for 4 weeks, then raise the dose by 2.5 mg no faster than every 4 weeks. For weight loss, the usual maintenance dose is 5, 10 or 15 mg. The KwikPen holds 4 weekly doses of one strength.

Sources

  1. DailyMed (NLM) — Zepbound (tirzepatide) prescribing information (rev. 8/2026)
  2. Lilly — Zepbound coverage, affordability and savings (self-pay KwikPen and vial pricing, savings card terms)
  3. Lilly — Mounjaro savings card terms
  4. Medicare.gov — Weight loss drugs (Medicare GLP-1 Bridge)
  5. KFF — Medicaid coverage of and spending on GLP-1s
  6. FDA — FDA's concerns with unapproved GLP-1 drugs used for weight loss
  7. FDA — FDA clarifies policies for compounders as national GLP-1 supply begins to stabilize