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Weight Loss Clinics and Doctors in St. Louis, MO

64 listed in St. Louis, MO · Listings last verified October 2026 · How we vet listings

We list 64 weight loss clinics and doctors in the St. Louis area, most of them in St. Louis, O'Fallon and Chesterfield. Each is a medical clinic or a clinician (MD, DO, NP or PA), shown with phone number, address and Google rating where we could match one. 18 say they offer telehealth visits. Use the filters to narrow your search.

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Renew Vitality Testosterone Clinic of St Peters

Weight Loss

Practice rating 5.0 (6 Google reviews)

Address
2730 S St Peters Pkwy, St. Peters 63303
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Saint Louis Medical Weight Loss, LLC

Weight Loss

Practice rating 4.7 (3 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
4455 Telegraph Rd Ste 260, St. Louis 63129
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Simply Wurth It Medical Weight Loss – O’Fallon

Weight Loss

Practice rating 4.8 (21 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
856 Waterbury Falls Dr, O'Fallon 63368
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Simply Wurth It Medical Weight Loss – South County

Weight Loss

Practice rating 5.0 (42 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
5139 Mattis Rd Suite 101, St. Louis 63128
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Simply Wurth It Medical Weight Loss – St. Peters

Weight Loss

Practice rating 5.0 (125 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
5301 Veterans Memorial Pkwy Ste 102, St. Peters 63376
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Simply Wurth It Medical Weight Loss – Wentzville

Weight Loss

Practice rating 5.0 (325 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
112 Creekside Office Dr, Wentzville 63385
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

South County Endocrinology and Obesity Medicine

Weight Loss

Practice rating 3.6 (15 Google reviews)

Address
12900 Tesson Ferry Rd Ste 101, St. Louis 63128
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

SSM Health Medical Group

Weight Loss

Practice rating 2.6 (5 Google reviews)

Address
711 Veterans Memorial Pkwy Ste 200, St. Charles 63303
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

SSM Health Weight Management Services

Weight Loss

Practice rating 5.0 (2 Google reviews)

Address
1011 Bowles Ave Ste 300, Fenton 63026
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

SSM Health Weight Management Services

Weight Loss

Practice rating 4.2 (28 Google reviews)

Address
12266 De Paul Dr Ste 210, Bridgeton 63044
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

SSM Health Weight Management Services

Weight Loss

Practice rating 1.0 (1 Google review)

Address
301 Caledonia Pkwy Ste 150, O'Fallon 63368
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Summit Rejuvenation Center

Weight Loss

Practice rating 5.0 (1 Google review)

  • Semaglutide
Address
5055 State Rte N #102, Cottleville 63304
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

Summit Rejuvenation Center – Wentzville

Weight Loss

Practice rating 4.5 (15 Google reviews)

  • Semaglutide
Address
1125 W Pearce Blvd, Wentzville 63385
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

The Health & Wellness Center

Weight Loss

Practice rating 4.7 (336 Google reviews)

  • Semaglutide
  • Tirzepatide
Address
9717 Landmark Pkwy Dr Ste 115, St. Louis 63127
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Oct 2026 Report a correction

In the St. Louis area

Our St. Louis listings cover the Missouri side of the metro: St. Louis County, St. Louis City, St. Charles County, Jefferson County, Franklin County and Lincoln County. Providers on the Illinois side, such as Belleville, Edwardsville and Alton, are listed under the Belleville–Metro East area.

Specialist care here is concentrated in a few large health systems: BJC HealthCare with Barnes-Jewish Hospital and Washington University physicians, Mercy, SSM Health and St. Luke's Hospital in Chesterfield. Each has clinics well beyond its main campus, so the same practice may have offices in the city, west St. Louis County and St. Charles County. Independent specialty groups practice alongside them, especially in Creve Coeur, Chesterfield and along the I-70 corridor in St. Peters, O'Fallon and Wentzville.

Most listings are in the City of St. Louis and St. Louis County, with a growing share in St. Charles County. If you live in Jefferson or Franklin County, check Festus and Washington before driving into the city.

Medical weight loss clinics in the area cluster in the City of St. Louis, O'Fallon, Chesterfield and Creve Coeur. Listings include physician-run clinics, hospital programs and franchise programs with medical staff. We don't list businesses that market compounded GLP-1 drugs.

Nearby: Belleville–Metro East, IL · Columbia–Jefferson City, MO · Cape Girardeau, MO

By town

How to choose a weight loss clinic

A medical weight loss clinic helps you lose weight under the care of a doctor, nurse practitioner or physician assistant. Care usually combines a nutrition and activity plan with regular check-ins, and sometimes prescription medicine such as a GLP-1 drug. Weight loss medicines work better when combined with a lifestyle program, not in place of one [1].

Look for real medical supervision. A good program starts with a full health history, a physical exam and often blood work. A licensed clinician should see you, decide whether medicine is right for you and follow up on side effects. Ask who you'll see at each visit and how often.

Check credentials. Many doctors who focus on weight care are certified by the American Board of Obesity Medicine. You can look up a doctor's certification on the ABOM website [2]. Our listings show the credentials providers report in the federal NPI registry or on their Google profile, but we don't verify board certification or licenses.

Ask how they prescribe GLP-1 medicines. Prescription weight loss medicine is usually for adults with a BMI of 30 or more, or 27 or more with a weight-related health problem such as high blood pressure or type 2 diabetes [1]. Ask which medicines the clinic prescribes, whether they use FDA-approved brand-name drugs, how they adjust your dose and what happens if you stop.

Watch for red flags. Be careful with any clinic that:

  • has no doctor, nurse practitioner or physician assistant on staff
  • promises a set amount of weight loss or "guaranteed" results
  • prescribes without reviewing your health history
  • pushes compounded semaglutide or tirzepatide as the same as the brand-name drug

Compounded versions are not reviewed by the FDA for safety, quality or effectiveness, and the FDA has warned companies whose ads made them sound FDA-approved [3]. We don't list businesses that market compounded GLP-1 drugs.

Understand cost and insurance. Ask what the program costs per month and what that includes: visits, lab work and the medicine itself are often billed separately. Some insurance plans cover weight loss medicines and some don't, so call your plan before you start [1]. Our guide to Zepbound insurance coverage explains how coverage and prior authorization work.

Know when not to wait. On a GLP-1 medicine, stomach pain that won't go away, especially pain that spreads to your back, with or without vomiting, can be a sign of a serious problem. Call your doctor right away or get emergency care [4].

Frequently asked questions

What does a medical weight loss clinic do?

A medical weight loss clinic treats weight as a health condition. A doctor, nurse practitioner or physician assistant reviews your health, sets goals and builds a plan that may include nutrition, activity, behavior support and prescription medicine. You'll usually have regular check-ins to track progress and side effects. We include a clinic only when its listing or website names medical staff.

Who qualifies for GLP-1 weight loss medicine?

In general, prescription weight loss medicine is for adults with a body mass index (BMI) of 30 or higher, or 27 or higher with a weight-related health problem such as high blood pressure or type 2 diabetes. A clinician decides whether it's safe for you based on your health history, other medicines and goals.

Are compounded semaglutide and tirzepatide safe?

Compounded drugs are made by pharmacies and are not reviewed by the FDA for safety, quality or effectiveness. The FDA has received reports of dosing errors with compounded semaglutide and has warned companies whose ads implied their products were FDA-approved. Ask your clinic whether it prescribes FDA-approved medicines. We don't list businesses that market compounded GLP-1 drugs.

Does insurance cover medical weight loss?

It varies. Some plans cover office visits and lab work but not weight loss medicines. Others cover the medicine only after prior authorization or if you have certain health conditions. Many clinics also offer self-pay programs. Call your insurance plan, then ask the clinic for a full price list before you sign up for any program.

What's the difference between a weight loss clinic and a diet program?

A medical weight loss clinic has licensed clinicians who can examine you, order tests and prescribe medicine. A diet program offers meal plans, coaching or products, but usually no medical care. We list only medical clinics and clinicians, and we leave out gyms, supplement sellers and diet programs without medical staff.

Sources

  1. NIDDK — Prescription medications to treat overweight and obesity
  2. American Board of Obesity Medicine — Find a physician / verify credentials
  3. U.S. Food and Drug Administration — FDA's concerns with unapproved GLP-1 drugs used for weight loss
  4. MedlinePlus — Semaglutide injection