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Hormone Replacement Therapy Providers in North Carolina

161 listed in North Carolina · Listings last verified November 2026 · How we vet listings

We list hormone therapy providers across North Carolina, mainly in Raleigh–Durham, Charlotte and Asheville (161 in total). Hormone replacement therapy (HRT) treats menopause symptoms like hot flashes and night sweats. Listings include OB/GYN and women's health practices and clinics that focus on menopause care. Compare the listings below, then call the practice to ask about insurance and new-patient openings.

Hormone therapy for menopause in North Carolina is offered by OB/GYN and women's health practices and by clinics that focus on hormone care. The largest groups are around Raleigh and Charlotte, with more in Wilmington, Hickory and Asheville. We list providers whose own website or Google listing names hormone therapy.

What it is

Hormone replacement therapy, also called menopausal hormone therapy, replaces the estrogen your body makes less of after menopause. It's the most effective treatment for hot flashes and night sweats [1].

There are two main types [1]:

  • Systemic therapy goes into your bloodstream. It comes as a pill, patch, gel, spray or vaginal ring, and treats hot flashes and other whole-body symptoms.
  • Low-dose vaginal estrogen treats vaginal dryness and pain with sex. Very little gets into your blood.

If you still have your uterus, you'll take a progestogen along with estrogen to protect against uterine cancer. If you've had a hysterectomy, estrogen alone may be used [1].

In 2026, FDA approved label changes that remove heart disease, breast cancer and dementia from the boxed warning on these products [3][4].

Who it's for

Hormone therapy is mainly for women with moderate to severe menopause symptoms. The Menopause Society says that for most women, the benefits outweigh the risks when therapy starts before age 60 or within 10 years of menopause [1].

Low-dose vaginal estrogen is an option for vaginal and urinary symptoms. Much less of the hormone reaches your blood [1].

HRT still has risks. These include blood clots and stroke, and a higher breast cancer risk after several years of use [1]. It may not be a good fit if you've had breast cancer, blood clots, a stroke or heart disease. Your provider will weigh your history and help you choose a type and dose.

If you can't or don't want to take hormones, non-hormone medicines are another option.

Cost and coverage

Estrogen and progesterone come in pills, patches, gels and rings, and many have generic versions. What you pay depends on your plan's drug list and the form you choose.

Commercial insurance. Each plan lists which forms it covers and at what cost. Ask your pharmacist or insurer what's on your plan's list before you fill.

Medicare. Prescription hormone therapy falls under Part D drug plans or Medicare Advantage plans with drug coverage. Each plan sets its own drug list and cost tiers. Generics are usually in the lowest-cost tier [6]. If a drug you need isn't covered, you or your provider can ask for an exception [6].

Patch supply. In September 2026, FDA said some estradiol patch brands were harder to find because demand went up. Patches are still available. Ask your pharmacist about switching to another FDA-approved patch [5].

Visit costs. Your office visit is billed like any other doctor visit. Some menopause clinics don't take insurance, so ask first.

For more, see our menopause guide and our Veozah savings guide for a non-hormone option.

Charlotte area

Long Health and Wellness PLLC

Menopause

Practice rating 5.0 (37 Google reviews)

  • Hormone Replacement Therapy
Address
2436 N Sharon Amity Rd Ste 102, Charlotte 28205
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Nov 2026 Report a correction

MediThrive Personalized Wellness

Menopause

Practice rating 5.0 (128 Google reviews)

  • Hormone Replacement Therapy
Address
19109 W Catawba Ave #120, Cornelius 28031
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Nov 2026 Report a correction

Miller Jr M Grant MD

Menopause

  • Hormone Replacement Therapy
Address
131 Medical Park Rd #102, Mooresville 28117
Telehealth
Practice offers telehealth
Medicare
Practice accepts Medicare
Medicaid
Not listed

Last verified Nov 2026 Report a correction

Opteluxe Wellness

Menopause

Practice rating 5.0 (79 Google reviews)

  • Hormone Replacement Therapy
Address
344 Rolling Hill Rd Ste 103, Mooresville 28117
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Nov 2026 Report a correction

Optimize U – Charlotte | Hormone Clinic

Menopause

Practice rating 5.0 (46 Google reviews)

  • Hormone Replacement Therapy
Address
3024-B Prosperity Church Rd, Charlotte 28269
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Nov 2026 Report a correction

PHC – Lake Norman Ob-Gyn

Menopause

Practice rating 4.6 (380 Google reviews)

  • Hormone Replacement Therapy
Address
131 Medical Park Rd #102, Mooresville 28117
Telehealth
Not listed
Medicare
Accepts Medicare
Medicaid
Not listed

Last verified Nov 2026 Report a correction

Piedmont HealthCare – Women’s Center

Menopause

Practice rating 4.4 (148 Google reviews)

  • Hormone Replacement Therapy
Address
1804 Davie Ave, Statesville 28677
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Nov 2026 Report a correction

Revita Medical

Menopause

Practice rating 4.9 (58 Google reviews)

  • Hormone Replacement Therapy
Address
8133 Ardrey Kell Rd Ste 201, Charlotte 28277
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Nov 2026 Report a correction

Signature Wellness

Menopause

Practice rating 4.9 (359 Google reviews)

  • Hormone Replacement Therapy
Address
3125 Springbank Ln STE A, Charlotte 28226
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Nov 2026 Report a correction

Signature Wellness

Menopause

Practice rating 4.0 (6 Google reviews)

  • Hormone Replacement Therapy
Address
1105 Spruce St #102, Belmont 28012
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Nov 2026 Report a correction

Simone Medical

Menopause

Practice rating 5.0 (76 Google reviews)

  • Hormone Replacement Therapy
Address
10806 Monroe Rd Unit B, Matthews 28105
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Nov 2026 Report a correction

Sorelle Health, PLLC

Menopause

Practice rating 5.0 (12 Google reviews)

  • Hormone Replacement Therapy
Address
135 S Sharon Amity Rd #208, Charlotte 28211
Telehealth
Not listed
Medicare
Not listed
Medicaid
Not listed

Last verified Nov 2026 Report a correction

Spartan Medical Associates, PC

Menopause

Practice rating 4.7 (65 Google reviews)

  • Hormone Replacement Therapy
Address
9820 Northcross Center Ct Suite 53, Huntersville 28078
Telehealth
Offers telehealth
Medicare
Not listed
Medicaid
Not listed

Last verified Nov 2026 Report a correction

How to choose a provider

Look for menopause training. Many OB/GYNs and primary care doctors prescribe HRT. Some have extra training. The Menopause Society certifies clinicians who pass its exam. Its online directory lets you search by ZIP code and telehealth [7]. Some of our listings show a "Menopause Society Certified" badge.

Ask about FDA-approved hormones. FDA-approved estradiol and progesterone are bioidentical, tested and labeled. Custom-compounded hormones, including pellets, aren't tested for safety or effectiveness and may not contain the dose prescribed [1][2]. Be cautious of clinics that sell only compounded products.

Expect a real conversation. A good provider asks about your symptoms, your health history and your family history. They should explain the risks for you, not just in general, and plan follow-up visits.

Confirm the basics yourself. Call to check insurance, new-patient openings and telehealth. We don't verify these.

Frequently asked questions

Is hormone replacement therapy safe?

For most healthy women who start before age 60 or within 10 years of menopause, The Menopause Society says the benefits outweigh the risks. Risks include blood clots, stroke and a higher breast cancer risk with longer use. Your own risk depends on your age, health and the type of HRT, so talk it through with a provider.

Did FDA remove the black box warning on HRT?

Mostly. In November 2025, FDA started removing heart disease, breast cancer and dementia from the boxed warning on menopausal hormone products. In February 2026, it approved the first updated labels. A warning about uterine (endometrial) cancer stays on systemic estrogen-alone products.

Are bioidentical hormones better?

Some FDA-approved hormones, like estradiol and progesterone, are bioidentical. They're tested and come with a label that lists risks. Custom-compounded "bioidentical" hormones aren't tested for safety or effectiveness. The Menopause Society says they may not contain the dose on the label and aren't safer than approved products.

Does Medicare cover hormone therapy?

Medicare drug plans (Part D) and Medicare Advantage plans with drug coverage cover prescription hormone therapy, but each plan has its own drug list and costs. Generics are usually cheapest. Check your plan's list before you fill, and ask your provider to request an exception if a needed drug isn't covered.

What kind of doctor prescribes HRT?

OB/GYNs, primary care doctors, nurse practitioners and menopause specialists can all prescribe hormone therapy. If your symptoms are complex or your doctor is unsure, look for a clinician certified by The Menopause Society. They've passed an exam on menopause care.

Sources

  1. The Menopause Society — Hormone therapy (patient education)
  2. The Menopause Society — 2022 Hormone Therapy Position Statement
  3. FDA — FDA approves labeling changes to menopausal hormone therapy products (February 12, 2026)
  4. HHS — Fact sheet: FDA initiates removal of boxed warnings from menopausal hormone therapy products (November 2025)
  5. FDA — Update on estradiol transdermal patch availability (September 3, 2026)
  6. Medicare.gov — What do drug plans cover?
  7. The Menopause Society — Choosing a healthcare practitioner